TRF2 Monoclonal Antibody (Clone 4A794.15)
Telomeric repeat binding factor (TRF2) is a ubiquitously expressed protein that is implicated in the control of telomere length.{18142} TRF2, like TRF1, contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes.{18142} TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini.{18143} The use of mutant forms of TRF2 has implicated a role of TRF2 in the prevention of senescence in primary human cells.{18143} Inhibition of TRF2 results in apoptosis in a subset of mammalian cell types.{18144}
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TRF2 Monoclonal Antibody (Clone 4A794.15)
13790-1
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TRF2 Monoclonal Antibody (Clone 4A794.15)
13790-1
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