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Absea Biotechnology
Absea – Advancing Protein Engineering and Mass Spectrometry Solutions
Absea is a leading innovator in protein engineering, mass spectrometry, and proteomics. Since its foundation in 2020, Absea has become a global leader in the life sciences, providing high-quality soluble proteins and monoclonal antibodies for various research and industrial applications. With cutting-edge technology and an expanding synthetic proteome portfolio, Absea serves the needs of scientists and industry pioneers worldwide.
Innovative Solutions in Proteomics
Absea offers an extensive portfolio of over 13,000 soluble proteins, covering 65% of the human proteome, and continues to expand its collection. Their state-of-the-art facilities in Berlin, China, and the Bay Area support a broad range of applications in AI-driven protein design, diagnostics, and drug development. By delivering reliable and advanced proteomics solutions, Absea has established itself as a trusted partner in scientific research.
Product portfolio
- Soluble proteins/antigens for proteomics and mass spectrometry
- Monoclonal antibodies for IHC/ICC, WB, IP, and more
- Antibody pairs and conjugates
- Isotope-labeled proteins for specialized research
- Oligoclonal™ antibodies – a groundbreaking antibody format
- Cross-linking mass spectrometry and proteomics services (XL-MS)
Oligoclonal™ Antibodies – A Revolutionary Approach
Absea’s Oligoclonal Antibodies are a novel class of antibodies that combine the benefits of both monoclonal and polyclonal antibodies. These products consist of two or more fully characterized monoclonal antibodies, mixed in precise proportions, to target different epitopes of the same antigen.
Advantages of Oligoclonal Antibodies
- High Reproducibility – Batch-to-batch stability and a defined and controllable formulation guarantees consistent performance across experiments.
- High Specificity – Each monoclonal antibody in the oligoclonal mixture targets a specific epitope of the antigen, thereby minimizing the risk of nonspecific binding.
- High Sensitivity – Oligoclonal Antibodies bind to multiple epitopes simultaneously, increasing sensitivity in detection and enabling analysis of low-abundance targets.
- Low Background – Compared to polyclonal antibodies, Oligoclonal Antibodies have reduced background noise, resulting in a higher signal-to-noise ratio that is ideal for various detection applications.
Cross-Linking Mass Spectrometry (XL-MS) – Unlocking Protein Interactions
Absea’s XL-MS service is a powerful tool for studying protein interactions and structural relationships under native conditions. Their advanced workflows allow researchers to analyze complex biological samples without requiring protein engineering or cell lysis, preserving the integrity of protein interactions.
Applications of XL-MS
- Mapping protein interactomes in diverse physiological and pathological conditions
- Identifying binding partners of clinically relevant proteins
- Discovering protein interactions for biomarker and drug target research
Supporting Advanced Proteomics Research
In addition to its core product offerings, Absea provides specialized mass spectrometry services, such as affinity purification-mass spectrometry (AP-MS), to characterize protein interactors. These comprehensive solutions enable researchers to gain critical insights into protein networks, advancing discoveries in proteomics, diagnostics, and drug development.
