Matreya LLC, Lipids and Biochemicals, a Cayman Chemical Company

Our supplier Cayman Chemical is known for their high quality biochemicals, assay kits, antibodies, and recombinant proteins and offer contract services for custom synthesis/analysis, assay development/screening, and drug discovery.
Their mission is to help make research possible. Therefore they continuously adding new (developed) products to their portfolio. Some of the products they have recently added are a broad range of Antibodies for glycolipids, Bacterial tetraethers, Ceramides and digydroceramides, D9 Glycolipids, Enzyme inhibitors for glycolipids, Fatty acids and methyl esters, Fluorescent standards, Gangliosides, Glycosyl Glycerides, Glycosphingolipids, Lipid mixtures, Plant sterols and steryl glucosides, Phospholipids, Phosphosphingolipids, Spingosines, Stable isotype labeled standards and Ocopherols and tocotrienols.

Antibodies for glycolipids

The antibodies are directed against the carbohydrate chains of ganglioside and globoside glycolipids. The same carbohydrate moieties are found on many glycoproteins. All antibodies are quality tested by actual ELISA and TLC immunoblotting analysis.

Products:
28638
28639
28640
28642
28644
28641

Bacterial tetraethers

Tetraether monosaccharide phospholipids (MPL) are the main phospholipids of Thermoplasma acidophilum. They contain a glycerophosphate and a gulosyl pyranoside monosaccharide linked via a tetraether chain. MPL is useful for making liposomes to study various molecular functions.

Products:
27203

Ceramides and digydroceramides

Ceramides and their saturated analogs dihydroceramides exert numerous biological effects including induction of cell maturation, cell cycle arrest, terminal cell differentiation, cell senescence, cell death, skin water-barrier function and protein regulation. These ubiquitous lipids can be used as standards for the analysis of tissues and identification and quantitation of major sphingolipids

Products:
Ceramides
Sphingosine

D9 Glycolipids

Deuterated glycolipids are ideal for the identification and quantification of glycolipids in samples and biological systems using mass spectrometry (LC-MS/MS) methods.

Products:
31195
31196
31198
31199

Enzyme inhibitors for glycolipids

Cayman Chemical offers inhibitors that will stop the enzymatic metabolism of glycolipids at various points in their biosynthetic routes. These include glucosylceramide synthase inhibitors PDMP and PPMP, Protein kinase C inhibitor Safingol, Acid and alkaline ceramidase inhibitors NOE and D-MAPP, and glucosidase inhibitor Conduritol B epoxide.

Products:
18624
10005276
17236
10005278
24525
24524
22676
10178
22677
24526

Fatty acids and methyl esters

Cayman Chemical offers a vast array of very high purity fatty acids and fatty acid methyl esters including saturated, polyunsaturated, trans-unsaturated, conjugated linoleic, conjugated linolenic, 2-hydroxy, 3-hydroxy, omega-hydroxy, branched methyl, and cyclopropyl. Many of these fatty acids have powerful biological effects.

Simply fatty acids and methyl esters
Conjugated linoleic Acids (VLA) and Methyl Esters
90140
31552
24581
90370
24580
24582
24583
90145
24584
Conjugated linolenic Acids (VLA) and Methyl Esters
24807
27098
10008333
Hydroxy Fatty Acids and Methyl Esters
2-hydroxy fatty acids and methyl esters
22678
24585
24586
24587
90390
24588
22679
24589
24590
24591
24592
24593
24594
24595
24597
24598
24599
24658
22680
3-hydroxy fatty acids and methyl esters
24607
24608
24609
24610
24611
24612
24613
24614
24640
24641
24642
24643
22689
24644
16871
24645
20108
28735
24646
22692
24647
Omega hydroxy fatty acids and methyl esters
24648
24649
24650
24651
24652
24653
24654
24655
24656
24657

Branched and Cyclic Fatty Acids and Methyl Esters
24809
24810
24812
24814
24816
24817
24819
24820
24821
24822
24823
24824
24825
26735
26736
Quantitative Fatty Acid Methyl Ester (FAME) Mixtures
298365
28665
28666
29366
28668
28669
28670
28645
28646
29352
29353
29354
28650
28651
29356
29357
29367
29368
29374
29375
29376
29377
24658
29370
29334
29335
29369
29336

Qualitative Fatty Acid Methyl Ester (FAME) Mixtures
28682
28681
28661
28662
28663
28683
29373
28679
28680
29363
29358
29359
29360
29361
29362

Fluorescent standards

Their fluorescent standards that can be detected in cultures and in biological systems, making them ideal for studies involving the metabolism of sphingolipids. These lipid analogs are very useful for determining the localization of various sphingolipids in membranes and organelles. The NBD fluorescent group attached to hexanoic acid has been shown to be readily taken up by cells and used in the biosynthesis of more complex sphingolipids.(Lipsky and Pagano J Cell Biol 1985)

Products:
24439
24330
24440
24441
24326
24327
24328
22830
22851
23209
24627
22828
22829
24628
33799
24470

Gangliosides

Gangliosides are acidic glycosphingolipids participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis, and metastasis. Cayman Chemical offers a number of high purity deuterated gangliosides which are ideal for mass spectrometry studies.

Products:
15586
24629
24837
24839
24840
33799
24838
31710
24849
31711
24850
31590
33263
24851
31591
31708
25487
31709
24852
31712
31561
24856
24857
29359
29362
29361
29362
33073
31195
31196
31198
31549
31551
31707
31593
31592
31562
34605
34778
15588
27202

Glycosyl Glycerides

Monogalactosyldiglyceride (MGDG) and digalactosyldiglyceride (DGDG) are two important biomolecules that are especially prevalent in chloroplast membranes and photosynthetic tissues, including those of algae and some bacteria. A proper ratio of MGDG and DGDG is critical for membrane function. MGDG plays an important role in the organization and activity of the embedded protein supercomplexes of the thylalkoid membrane of photosystem II and it helps to maintain an optimum lipid to protein ratio. DGDG forms a lipid bilayer in the lipid membrane whereas MGDG does not.

Products:
17886
27373

Glycosphingolipids

Glycosphingolipids affect apoptosis, cell proliferation, endocytosis, intracellular transport, cell migration and senescence, and inflammation. Cayman Chemical produces galactosylceramides, glucosylceramides, sulfatides (sulfo-galactosylceramides), lactosylceramides, globotriaosylceramides (ceramide trihexosides), globosides, and gangliosides. Each of these are available with natural fatty acids as well as with specific well-defined fatty acids in the ceramide moiety

Products:
Galactosylceramide
Glucosyl
Sulfatide
Lactosylceramide
Trilhexosides
Globoside
Ganglioside

Lipid mixtures

Benefits of knowing the fatty acid content of bacteria include understanding microbes and animal nutrition. Microbial fatty acid profiles are unique from one species to another and can therefore be used in the determination of bacterial identity. Cayman offers a wide selection of fatty acid methyl ester and glycosphingolipid mixtures. Each methyl ester mixture is carefully prepared by weight and the composition is verified by gas chromatography and TLC.

Products:
29365
28665
28666
29366
28668
28669
28670

Biochemical Research standard mixes

Products:
29374
29375
29376
29377

Carbohydrate mixtures

Products:
29367
29368

Food industry Mixtures

Products:
29371
29334
29335
29369
29336

GLC standard mixtures

Products:
28645
28646
29352
29353
29354
28650
29355
29356
29357
29372

Glycosphingolipid reference mixture for TLC

Products:
29358
29359
29360
29361
29362
24856
24857

Microbiology standards

Products:
28682
28681

Products:
29372
29373

Polyunsaturated fatty acid methyl ester mixtures

Products:
28661
28662
28663

Water soluble fatty acid mixtures

Products:
28679
28680

Plant sterols and steryl glucosides

Cayman Chemical offers a line of cholesterols, phytosterols, and steryl glucosides which comprise an important lipid category of cholestane derivatives. Plant sterols will complex with glycosphingolipids in raft-like sub-domains and can affect many cellular functions including membrane fluidity, permeability, activity of membrane-bound enzymes, cellular differentiation, cellular signaling, and cellular proliferation.

Products:
29364
28643
27205
27204

Phospholipids

Phospholipids are well known for their role as the main component of membranes, but are also important as cellular messengers, enzyme activators, and more. Hundreds of different phospholipid molecular species are present in cells, each having variations in their phospholipid head-group or acyl tails that give them unique properties. Cayman Chemical offers an extensive list of highly purified natural and synthetic phospholipids including phosphatidylcholine, phosphatidic acid, phosphatidylethanolamine, phosphatidylserine, phosphatidylinositol, phosphatidylglycerol, and phosphosphingolipids.

Products:
Natural phospholipids
24343
24370
24331
24341
33671
24523
24344
24332
16878

Phosphosphingolipids

Phosphosphingolipids are important lipids that function as cellular messengers, enzyme activators, and more.

Products:
22674
31558
31559
24345
24353
24354
24355
24450
24451
24452
24453
9003457
9003460
9003459
9003463
10007947
24454
31557
24463
24328
22542
24464

Spingosines

Sphingolipids are widely distributed in animal and plant tissues, particularly in cell membranes where they serve numerous vital cellular functions. Cayman Chemical offers several isomers of sphingosine as well as a number of sphingosines with various chain lengths, deuterium labels, and fluorescence probes.

Products:
24371
26893
24373
24371
18624
24374
24375
24367
24376
22509
24378
24380
24381
22824
24384
20217
28933
28934
29919
27199
22827
9003465
24385

Stable isotype labeled standards

Stable isotope standards can be easily detected by mass spectrometry while demonstrating nearly identical physical properties to natural sphingolipids. This is very important to ensure similar extraction properties and signal response between the analytes and the internal standards.

Products:
24371
24396
24423
24452
9003461
24467
24621
24624
24625
24626
24839
24849
24850
24852
24464
31195
31196
31198
9003460
9003462
9003463

Ocopherols and tocotrienols (Vitamin E)

Vitamin E has become well known for its role as an antioxidant, in lowering levels of cholesterol and other lipids, as a neuroprotective and anti-cancer agent, and in cardiovascular disease protection. It consists of four tocopherols and four tocotrienols which have important and far-reaching biological activities. These essential lipids contain a common chromanol ring and either a saturated (tocopherol) or unsaturated (tocotrienol) side chain.

Tocopherols
26758
27193
31589
27194
27195
Tocotrienols
10008377
9001533
10008494
10008513