Sanbio works together with a wide variety of suppliers. In addition to their products, our suppliers offer a wide variety of custom services. These services range from antibody engineering and sequencing to exosome, CRISPR/Cas9, gene delivery and expression services. Respectively these services are performed by Absolute antibody and System Biosciences. Please see below for a detailed explanation of the custom services that these suppliers have to offer.
System Biosciences
When time is of the essence and your project needs outside expertise and resources, SBI’s services team is ready to help. The same scientists that devote their days to building the highly-regarded products also deliver the custom services.
Exosome Services
When you choose SBI’s Exosome Services, you get more than high-quality exosome production or simple data delivery, you get in-depth scientific and technical support on everything from project planning to data interpretation from scientists with years of exosome experience. Exosome service: Exo-NGS, Exosome Proteomics Services, Exosome Lipidomics & Metabolomics Services, NTA-based Exosome Characterization, Exosome Isolation & Manufacturing or Exosome Engineering.
CRISPR/Cas9 Services
From start to finish, SBI’s CRISPR/Cas9 Services can cover all or just part of your entire genome engineering workflow. Services like: CRISPR/Cas9 gRNA and HR Donor Cloning or CRISPR/Cas9 Cell Line Engineering.
Syn2Clone Custom Constructs
With SBI’s highly affordable Syn2Clone service, you can order any of SBI’s well-validated and highly published vectors with your gene-of-interest already in it.
Lentivirus Packaging
When it comes to cell line engineering with lentivirus, getting high-quality, high-titer lentivirus preparations is often critical for success, especially with hard-to-transduce cell lines. And when it comes to getting high-quality, high-titer lentivirus, you can reliably turn to the Lentivirus Packaging team at SBI.
Stable Cell Lines
Whatever your custom cell line needs, whether it’s for reporter cells that express GFP, or luciferase for high-throughput assays, overexpression cells to study your protein-of-interest, or customized cells for any research application, SBI’s Stable Cell Line Services are ready to deliver.
Minicircle Services
When you want sustained transgene expression without the risks of introducing exogenous DNA, minicircle technology is a great option. But many labs don't have either the time to spend constructing and producing minicircles or the in-house expertise. Which is why SBI offers Custom Minicircle Services.
RNA Services
Whether you want to get fast protein expression by transfecting or injecting mRNA into cells or are studying regulatory RNAs through profiling, overexpression, or knockdowns, the SBI team is ready to support your studies with their custom RNA synthesis services.
Absolute Antibody
Absolute Antibody specializes in the sequencing, engineering, and recombinant production of antibodies.
Antibody Sequencing
Good, validated antibodies are highly valuable, but hybridomas are easily lost. Storage accidents, genetic drift or contamination can threaten the security of your antibody.
One solution is to sequence your antibody to enable recombinant production. Sequencing an antibody is vital when obtaining intellectual property rights for your sequence, and expands your antibody’s potential with antibody engineering options.
Hybridoma sequencing
The hybridoma sequencing service of Absolute Antibody is the starting point for protecting your antibody and embarking on antibody engineering projects such as species-, isotype- and subtype-switching or even humanization.
Antibody Protein sequencing
Sometimes however, it is too late for hybridoma sequencing as the cell line has been lost or is otherwise unavailable. If sufficient protein is still available, advances in mass-spectrometry technology have made it possible to sequence the protein.
Polyclonal antibody sequencing
Sequencing polyclonal antibodies in order to secure precisely defined and reproducible source of antibodies has been impossibility, until now. In partnership with Digital Proteomics, Absolute Antibody is offering a polyclonal antibody immortalization service.
Antibody Engineering
At Absolute Antibody they have developed a proprietary cloning system to enable rapid reformatting of antibodies into almost any format. The antibody engineering services include chimerization, humanization, isotype switching and the manufacturing of recombinant antibody fragments and bispecific antibodies.
Antibody Expression / Antibody Production
Absolute Antibody’s HEXpress service was launched to meet the growing demands for recombinant antibodies across research and diagnostics. This proprietary transient expression system allows Absolute Antibody to manufacture milligram to gram quantities of antibody in mammalian HEK293 cells and is a faster, more affordable alternative to stable CHO cell line generation with higher quality and flexibility than traditional hybridoma production. Simply provide them with an electronic sequence or hybridoma cell line and they take care of the rest. They even guarantee the quantity and quality of the antibody for all your in vitro or in vivo needs. Antibody production upon your request!