The use of high-purity lipids is crucial for the successful formation of Lipid Nanoparticles (LNPs). At Sanbio, we provide premium lipids sourced from our trusted supplier, Cayman Chemical. Their extensive and continually expanding catalog features ready-made lipids ideal for LNP formation, including Cationic Lipids, Helper Lipids, PEGylated Lipids, and Sterol Lipids.
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Lipids for Forming Lipid Nanoparticles (LNPs)
Cationic Lipids
Cationic lipids, both fixed and ionizable, are used in LNPs to encapsulate nucleic acids and promote endosomal escape. Learn more about the efficacy and safety of ionizable cationic lipids on the Cayman Chemical website.
Helper Lipids
Helper Lipids are used to modify the net surface charge of LNPs. Anionic lipids contribute to aggregation during storage, while neutral phospholipids play a key role in membrane fusion.
PEGylated Lipids
PEGylated lipids prevent opsonization, enhancing particle stability and increasing bioavailability.
Sterol Lipids
Sterol lipids provide stability to LNPs and facilitate membrane fusion and endosomal escape.
For a complete overview of lipid components for drug delivery, visit the Cayman Chemical website. You can refine your search based on lipid type and research area. If you have any questions, please contact our technical support at support@sanbio.nl.
For more insights into optimizing LNP formulation, don’t miss our comprehensive LNPs Formulation Guide blog.