PKC? Inhibitor Peptide

Protein kinase C? (PKC?) is a calcium-independent, phospholipid- and diacylglycerol-dependent serine/threonine kinase involved in diverse signaling pathways, including those involved in neuronal signaling, cytoskeletal function, and inflammation.{9056} PKC? inhibitor peptide is a synthetic peptide corresponding to an amino acid sequence found in the amino terminal C2 domain of most mammalian forms of PKC?.{28594} It selectively and reversibly inhibits the translocation of PKC? to intracellular membranes, blocking activation.{28594} PKC? inhibitor peptide is commonly used in cells to evaluate the role of PKC? in various cellular responses.{28596,28597,28595}