Anti-Isocitrate Dehydrogenenase 1 (IDH1)-R132S, R132S, Mouse, Monoclonal, ready to use
Isocitrate dehydrogenase 1 (IDH1) is a 46 kDa NADPdependent enzyme, which catalyzes the decarboxylation of isocitrate into ?-ketoglutarate. IDH1 may also play a role in the prevention of oxidative damage, and the shuttling of proteins to peroxisomes. It is widely reported that mutations in IDH1 result in multiple forms of gliomas. The Arginine to Serine substitution at amino acid 132 is seen in gliomas, abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate..
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Anti-Isocitrate Dehydrogenenase 1 (IDH1)-R132S, R132S, Mouse, Monoclonal, ready to use
PDM582R
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Anti-Isocitrate Dehydrogenenase 1 (IDH1)-R132S, R132S, Mouse, Monoclonal, ready to use
PDM582R
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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