Mouse anti Cytomegalovirus gB Late Neutralizing Antigen antibody, clone HCMV37 recognizes Cytomegalovirus glycoprotein B late neutralizing antigen. Cytomegalovirus is an enveloped double stranded DNA virus which in humans (HCMV) is commonly known as human herpesvirus 5 (HHV-5).
Glycoprotein B (gB) is the main antigenic protein within the envelope of HCMV. It is required for HCMV mediated membrane fusion along with the gH / gL complex. The unprocessed precursor of HCMV gB is 906 amino acids in length, with a MW of approximately 100 kDa.Mouse anti Cytomegalovirus gB Late Neutralizing Antigen antibody, clone HCMV37 reacts with MRC-5 infected cells but not uninfected cells. This antibody has been found to be neutralizing.