Rabbit anti-PAX2, clone EP3251 (Monoclonal)
PAX2 is a transcription factor that plays a key role during renal development and angiogenesis and through the Act-survival pathway (1). PAX2 is also expressed in normal renal medulla where it is regulated by the normally high and variable NaCl concentration, and it protects renal medullary cells from high NaCl concentration-induced apoptosis (2). Recent reports show that PAX2 also plays a role in breast cancer by competing with the ER co-activator AIB-1/SRC-3 for the binding and regulation of ERBB2 transcription (3). PAX2 is expressed in primitive cells of the kidney, ureter, eye, ear and central nervous
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Rabbit anti-PAX2, clone EP3251 (Monoclonal)
MON10213
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Rabbit anti-PAX2, clone EP3251 (Monoclonal)
MON10213
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