MCOPPB (hydrochloride hydrate)
The nociceptin/orphanin FQ peptide (NOP, ORL1, or OP4) receptor is a member of the opioid family of receptors that integrates the emotional components of anxiety, fear, and stress. MCOPPB is a potent agonist for the NOP receptor (pKi = 10.1, EC50 = 0.39 nM) with 12-, 270-, and >1,000-fold selectivity over the ?-, ?-, and ?-opioid receptors.{22070,22071} In rodents, MCOPPB at 10 mg/kg, p.o. produces potent anxiolytic effects, without inhibiting memory or motor function or inducing sedative side effects.{22070} This product is intended for research purposes only.
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MCOPPB (hydrochloride hydrate)
12037-5
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