Product description
Rat anti Mouse CD49d monoclonal antibody, clone PS/2 recognizes murine alpha 4 integrin (CD49d), a ~150 kDa single pass type I membrane glycoprotein that can associate with either beta 1 integrin (CD29) or beta 7 integrin to form heterodimers CD49d/CD29 (VLA-4) and alpha4/beta7 (LPAM-1) respectively (Holzmann et al. 1989). CD49d is expressed on most lymphocytes, granulocytes, monocytes and thymocytes. The primary ligands for CD49d are CD106 (VCAM-1), fibronectin and MAdCAM-1 (Sheppard et al. 1994).Clone PS/2 has also been reported to block the binding of CD49d to its ligands (Andrew et al. 1994).
Specifications
Host
Rat
Clonality
Monoclonal
Clone
PS/2
Supplier
Bio-Rad
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C

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Rat Anti-Mouse CD49d Alexa fluor 647

MCA1230A647

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Rat Anti-Mouse CD49d Alexa fluor 647

MCA1230A647

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