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Anti-HVEM mAb
K0031-3
100 ug
€476
Product description
Herpes virus entry mediator (HVEM)
is a member of the tumor necrosis factor receptor (TNFR)
superfamily that has a role in herpes simplex virus entry, in
T cell activation and in tumor immunity. HVEM is
constitutively expressed on CD4+ and CD8+ T cells, CD19+
B cells, CD14+ monocytes, neutrophils and dendritic cells
(DCs). The cytoplasmic region of HVEM binds to several
members of the TNFR-associated factor (TRAF) family,
namely, TRAF1, TRAF2, TRAF3 and TRF5, but not to
TRAF4 or TRAF6, and that it activates transcription factors
NF-?B and AP-1. The co-expression of glycoprotein D
(gD) and HVEM results in the inhibition of the NF-?B
activation that is induced by the HVEM overexpression.
Specifications
Applications
FC
Host
Mouse
Clonality
Monoclonal
Clone
122
Supplier
MBL International
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
-20°C
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Anti-HVEM mAb
K0031-3
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Anti-HVEM mAb
K0031-3
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