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Filibuvir
HY-10118-1
1 mg
€96
Product description
Contact us for other availabe units
Filibuvir is an orally active, selective non-nucleoside inhibitor of the HCV nonstructural 5B protein (NS5B) RNA-dependent RNA polymerase (RdRp). Filibuvir binds noncovalently in the thumb II allosteric pocket of NS5B. Filibuvir inhibits genotype 1a and 1b replicons with EC50s of 59 nM for both isoforms, respectively. Filibuvir preferentially inhibits elongative RNA synthesis and potently decreases viral RNA accumulation.
Specifications
CAS number
877130-28-4
Supplier
MedChem
Shipping & storage
Shipping condition
Room Temperature
Storage temperature
-20°C
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Filibuvir
HY-10118-1
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Filibuvir
HY-10118-1
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