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Pactimibe
HY-100401-5
5 mg
€540
Product description
Contact us for other availabe units
Pactimibe (CS-505 free base) is a dual ACAT1/2 inhibitor with IC50s of 4.9 ?M and 3.0 ?M, respectively. Pactimibe (CS-505 free base) inhibits ACAT with IC50s of 2.0 ?M, 2.7 ?M, 4.7 ?M in the liver, macrophages and THP-1 cells, respectively. Pactimibe (CS-505 free base) noncompetitively inhibits oleoyl-CoA with a Ki value of 5.6 ?M. Moreover, Pactimibe (CS-505 free base) obviously inhibits cholesteryl ester formation with an IC50 of 6.7 ?M. Pactimibe (CS-505 free base) possesses anti-atherosclerotic potential with lowering plasma cholesterol activity.
Specifications
CAS number
189198-30-9
Supplier
MedChem
Shipping & storage
Shipping condition
Room Temperature
Storage temperature
2-8°C
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Pactimibe
HY-100401-5
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