Histone H4 (human, recombinant)
A nucleosome is the basic repeating unit of chromatin in which 146 base pairs of DNA wrap twice around a histone octamer consisting of two copies of each of the core histones, H2A, H2B, H3, and H4.{17798} The combination of two H2A/H2B dimers and one H3/H4 tetramer create the nucleosome core.{17953} Histone H4 undergoes many modifications which include acetylation, methylation, and phosphorylation that are important for regulation of gene transcription.{17798}
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