Histone H3K4Me1 Monoclonal Antibody
Histone H3 is a nuclear protein and a component of the nucleosome core, a basic unit of chromatin, that is essential for organizing genomic DNA in eukaryotic nuclei.{57056} It is a globular protein that contains an unstructured N-terminal tail that extends outside of the nucleosome core and is subject to various post-translational modifications (PTMs), including methylation, phosphorylation, acetylation, and citrullination.{57056,53978} Monomethylation of histone H3 at lysine 4 (H3K4Me1) is found at active and primed enhancer regions of gene promoters and H3K4Me1-containing nucleosomes are more efficiently remodeled by the chromatin-remodeling complex BAF than unmarked nucleosomes.{48250,48251} It is also enriched at CpG sites associated with aging in stem and differentiated cells.{48252} Cayman's Histone H3K4Me1 Monoclonal Antibody can be used for chromatin immunoprecipitation (ChIP), ELISA, immunocytochemistry (ICC), multiplex-based assay, and Western blot (WB) applications.
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Histone H3K4Me1 Monoclonal Antibody
32131-100
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Histone H3K4Me1 Monoclonal Antibody
32131-100
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