(S)-(+)-Methoprene
(S)-(+)-Methoprene is a widely-used insect growth regulator.{27670} It is remarkable for its lack of significant effects against a wide variety of mammals, although concerns remain for its effects on arthropod development.{27670,27671} Methoprene acts as an activator of the juvenile hormone receptor, known as Methoprene-tolerant or Met (Kd = 12.3 nM).{27673,27669} Met is a transcription factor that, upon activation with juvenile hormone or methoprene, regulates gene expression that inhibits metamorphosis.{27672}
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