C16 Lactosylceramide (d18:1/16:0)
C16 Lactosylceramide is an endogenous bioactive sphingolipid.{41044} It forms membrane microdomains with Lyn kinase and the ?i subunits of inhibitory G protein-coupled receptors (GPCRs), suggesting a role in cell signaling. Plasma levels of C16 lactosylceramide are elevated in insulin-resistant cattle.{38685} C16 Lactosylceramide is also upregulated in a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder.{40751} [Matreya, LLC. Catalog No. 1532]
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