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NSC-663284
C04-902-5
5 mg
Price on request
Product description
Potent, selective and irreversible inhibitor of CDC25 phosphatases, Ki=29, 95 and 89 nM for human CDC25A, B2 and C respectively and >20- and >450-fold selective over VHR and PTP1B1. Arrests cells at G1 and G2/M and inhibits cdk1 and 2 activation2. Inhibits the growth of a variety of human tumor cell lines3. Acts via irreversible oxidation of the catalytic cysteine of CDC254.
Specifications
CAS number
383907-43-5
Supplier
SignalChem
Shipping & storage
Shipping condition
Room Temperature
Storage temperature
-20°C
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Productname
NSC-663284
C04-902-5
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