Anti-SLC40A1 (FPN1) (Human) pAb

SLC40A1, also known as ferroportin 1, belongs to the iron-regulated transporter family and absorbs iron from the diet into the bloodstream through the small intestine. The absorbed iron binds to transferrin in the blood and is then carried to tissues and organs throughout the body. SLC40A1 also transports iron out of reticuloendothelial cells, which are phagocytic immune cells present in the liver, spleen, and bone marrow. Mutations in the SLC40A1 gene cause hemochromatosis, which is characterized by impaired iron regulation and disorders associated with ir on deficiency or overload.