Anti-SLC7A9 (B0,+AT) (Human) pAb
SLC7A9, also known as B0,+- type amino acid transporter (B0,+AT), is a member of the cationic amino acid transporter/glycoprotein-associated family, and it functions as a heterodimer with the amino acid transport protein SLC3A1/rBAT. The SLC7A9 protein is predominantly distributed in the kidney, small intestine, liver, and placenta. Defective mutations in the SLC7A9 and/or SLC3A1 gene cause cystinuria, which is characterized by impaired transport of cystine and dibasic amino acids through the epithelial cells of the renal tubule and gastrointestinal tract; this results in the formation of calculi due to cystine precipitation in the urinary tract, leading to obstruction, infections, and ultimately, renal insufficiency.
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Anti-SLC7A9 (B0,+AT) (Human) pAb
BMP021
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Anti-SLC7A9 (B0,+AT) (Human) pAb
BMP021
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