BRSK1 is serine/threonine kinases 1 which required for presynaptic differentiation in Caenorhabditis elegans that are needed for neuronal polarization (1). BRSK1 is highly expressed in all specific adult brain regions followed by fetal brain and adult spinal cord. It is also expressed in adult heart, pancreas, testis, ovary, lung, and kidney, and in fetal liver (2).