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anti-CCM2 antibody
ARG64074100
100 ug
€691
Product description
This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]
Specifications
Applications
FC, WB, IF, ICC
Host
Goat
Clonality
Polyclonal
Isotype
IgG
Supplier
Arigo Biolaboratories Corporation
Shipping & storage
Storage temperature
-20°C
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anti-CCM2 antibody
ARG64074100
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anti-CCM2 antibody
ARG64074100
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