Product description
This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. [provided by RefSeq, Jul 2012]
Specifications
Applications
WB
Host
Goat
Clonality
Polyclonal
Isotype
IgG
Supplier
Arigo Biolaboratories Corporation
Shipping & storage
Storage temperature
-20°C

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anti-GRAP antibody

ARG63124100

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anti-GRAP antibody

ARG63124100

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