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anti-CD33 antibody (WM53) (PE)
ARG54314050
50 tests
€450
Product description
CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia.
Specifications
Applications
FC, IHC-Fr, WB, IF, ICC
Host
Mouse
Clonality
Monoclonal
Clone
WM53
Isotype
IgG1, kappa
Supplier
Arigo Biolaboratories Corporation
Shipping & storage
Storage temperature
2-8°C
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anti-CD33 antibody (WM53) (PE)
ARG54314050
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anti-CD33 antibody (WM53) (PE)
ARG54314050
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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