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Product description
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Jul 2008]
Specifications
Applications
WB, IF, ICC
Host
Rabbit
Clonality
Polyclonal
Shipping & storage
Storage temperature
-20°C
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Productname
anti-PDX1 antibody
ARG40125100
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Productname
anti-PDX1 antibody
ARG40125100
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