Product description
External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007 [PubMed 17317631]).[supplied by OMIM, Jan 2010]
Specifications
Applications
WB
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Supplier
Arigo Biolaboratories Corporation
Shipping & storage
Storage temperature
-20°C

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anti-POLK / DNA Polymerase Kappa antibody

ARG40004100

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Productname

anti-POLK / DNA Polymerase Kappa antibody

ARG40004100

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