Legenda image
Western blot: 1. Untreated HeLa cell 2. UV-traeted HeLa cell stained with ARG20150 anti-p53 phospho (Ser15) antibody. The antibody detects ~53 kDa Ser15 phosphorylated p53. It does not react with non-phosphorylated p53 or p53
Product description

Human HDAC6 (1215 a.a. residues) possesses two separate putative catalytic domains, both of which are fully functional and contribute independently to the overall activity of HDAC6. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. HDAC6 may participate in coordinating expression of a group of genes involved in the remoldeling of chromatin during cell differentiation.

Specifications
Applications
IHC, WB
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Supplier
Arigo Biolaboratories Corporation
Shipping & storage
Storage temperature
-20°C

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anti-HDAC6 antibody

ARG20183050

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anti-HDAC6 antibody

ARG20183050

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