Legenda image
Immunocytochemistry: HEK293 cells stained with ARG10549 anti-Akt 1 phospho (Ser473) antibody [X20-A] at 1:300 dilution.
Product description

Bax belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. The association and the ratio of BAX to BCL2 also determines survival or death of a cell following an apoptotic stimulus. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Dec 2019]

Specifications
Applications
IP, IHC-P, WB, IF, ICC
Host
Rabbit
Clonality
Monoclonal
Clone
G26-R
Isotype
IgG
Supplier
Arigo Biolaboratories Corporation
Shipping & storage
Storage temperature
-20°C

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anti-Bax antibody (G26-R)

ARG10552050

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anti-Bax antibody (G26-R)

ARG10552050

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