anti-CD71 / Transferrin Receptor antibody (23D10)
The functions of Transferrin Receptor is: cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. [Provide by uniprot]
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anti-CD71 / Transferrin Receptor antibody (23D10)
ARG10482250
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anti-CD71 / Transferrin Receptor antibody (23D10)
ARG10482250
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