anti-TGF-alpha mouse monoclonal, 1E8-G6, purified
1E8-G6 reacts with TGF-alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. 1E8-G6 is completely blocked by the peptide used for immunization. TGF-alpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype. In sections both cytoplasma and cell membranes are stained. Positive control: Jurkat or Ramos cells. testicular carcinoma, breast cancer.
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anti-TGF-alpha mouse monoclonal, 1E8-G6, purified
691508
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anti-TGF-alpha mouse monoclonal, 1E8-G6, purified
691508
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