anti-Proliferation Marker mouse monoclonal, IPO-38, purified
IPO-38 reacts with a 12-14 kDa protein, as found in Western blots of Raji cells, and appears in the mitotic cycle earlier than Ki-67. Lymphocytes, induced to early G1 phase by 12h exposure to PHA, will become positive while non-stimulated lymphocytes remain negative. Mononuclear cells and granulocytes of healthy donors are negative, while various forms of leukemia and lymphoma including Hodgkin’s disease are positive for IPO-38, as are many solid tumors such as some breast, gastric and colonic cancers for which it may serve as tumor progression marker. Positive control: Raji cells.
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anti-Proliferation Marker mouse monoclonal, IPO-38, purified
691701
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anti-Proliferation Marker mouse monoclonal, IPO-38, purified
691701
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