8B8 specifically reacts with the 85 kD beta-chain of human LRP/alpha-2MR which is expressed in a restricted spectrum of cell types (Herz & Strickland 2001). A strong immunohistochemical reaction is seen in hepato-cytes, tissue macrophages, subsets of neurones and as-trocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in athero-sclerotic lesions in the arterial wall. The antibody can also be used for the characterization of a subset of myelo-monocytic subtypes of chronic and acute leukemia (CD 91). Herz J and Strickland DK: LRP, a multifunctional scavanger and signaling receptor. J. Clin. Invest. 108, 779-784 (2001)
Productname
anti-LRP, 85kD, CD91, 8B8, purified IgG1
61067
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Productname
anti-LRP, 85kD, CD91, 8B8, purified IgG1
61067
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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