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Anti-Hu CD244 APC
1A-870-T100
100 tests
€290
Product description
CD244 is a 70 kDa type I transmembrane glycoprotein containing four ITSM domains in its cytoplasmic part, serving as docking sites for both activating and inhibitory signaling molecules. Its extracellular ligand is CD48. CD244 is involved in non-MHC restricted cytotoxic activity of NK cells and acts as a costimulatory ligand for both NK cells and T cells. Interaction of CD244 with CD48 on T cells leads to the activation of both, but interaction with CD48 on other cells (e.g. tumor cells) can lead to inhibition of NK cell functions.
Specifications
Applications
FC
Host
Human
Clone
2-69
Isotype
Mouse IgG2a kappa
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C
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Anti-Hu CD244 APC
1A-870-T100
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Anti-Hu CD244 APC
1A-870-T100
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