Rabbit anti p27/Kip1 (pThr187) antibody recognizes p27/Kip1, also known as cyclin-dependent kinase inhibitor p27 or cyclin-dependent kinase inhibitor 1B, when phosphorylated at threonine 187. p27/Kip1 is a cyclin-dependent kinase inhibitor (CKI) that belongs to the Cip/Kip protein family (Cerqueira et al. 2014). p27/Kip1 inhibits cyclin-dependent kinases (CDKs) and cyclin-CDK complexes; playing a role in the regulation of cell cycle progression at G1 (Cerqueira et al. 2014). Phosphorylation of p27/Kip1 at threonine 187 by CDK2 leads to the ubiquitination and subsequent degradation of p27/Kip by the 26S proteosome (Das et al. 2016).
Productname
RABBIT ANTI p27/Kip1 (pThr187)
AHP2662
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Productname
RABBIT ANTI p27/Kip1 (pThr187)
AHP2662
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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