RABBIT ANTI LCK (pTyr394)
Rabbit anti LCK (pTyr394) antibody recognizes LCK, also known as tyrosine-protein kinase Lck, leukocyte C-terminal Src kinase, lymphocyte cell-specific protein-tyrosine kinase or p56-LCK, when phosphorylated at tyrosine 394. LCK is a member of the Src family of tyrosine kinases. The T cell antigen receptor (TCR) depends on LCK to initiate signaling.LCK is autophosphorylated at tyrosine 394 in response to TCR engagement (Wright et al. 1994). Phosphorylation of LCK at tyrosine 394 leads to phosphorylation of CD3 and the gamma chains of the TCR as part of T cell activation.
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AHP2640
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