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Rabbit Anti-CDKN2A
AHP1488
0,1 mg
€363
Product description
Rabbit anti Human CDKN2A antibody recognizes human cyclin-dependent kinase inhibitor 2A (CDKN2A), a 16 kDa protein belonging to the CDKN2 cyclin dependent kinase inhibitor family.
CDKN2A acts as a negative regulator of cell proliferation by interacting strongly with CDK4 and CDK6, thus inhibiting their ability to interact with cyclin D and to phosphorylate the retinoblastoma protein.
CDKN2A is an important tumour suppressor and defects in its production results in tumour formation in a wide range of tissues, including cutaneous malignant melanoma and Li-Fraumeni syndrome.
Specifications
Applications
IHC, WB
Host
Rabbit
Clonality
Polyclonal
Supplier
Bio-Rad
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C
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Productname
Rabbit Anti-CDKN2A
AHP1488
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Rabbit Anti-CDKN2A
AHP1488
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