Product description

Rabbit anti Human SMAD3 antibody recognizes Mothers against decapentaplegic homolog 3 (SMAD3), a 50 kDa transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase, SMAD3 functions in cell proliferation, differentiation and development. Upon stimulation, SMAD3 oligomerizes with SMAD4 and translocates into the nucleus where it binds to DNA and transcription factors. SMAD3 activity induces differentiation of selected neuronal subtypes at the expense of other subtypes.Defects in SMAD3 may be a cause of colorectal cancer (Sjöblom et al. 2006).

Specifications
Applications
IHC, WB, ELISA
Host
Rabbit
Clonality
Polyclonal
Supplier
Bio-Rad
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C

Order your product by email

Productname

Rabbit Anti-SMAD3

AHP1465

By filling out this form, you are placing an order by e-mail. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.


Request a sample

Productname

Rabbit Anti-SMAD3

AHP1465

By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.


Organization information

*Required fields


Are you looking for specific products, alternatives or documentation?