AMHR2 Protein

AMHR2 is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins which bind the ligand on their own but require the presence of a type I receptor for signal transduction. AMHR2 encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone which results in male sex differentiation and produced in the testes by different cells and has different effects (1). AMHR2 may be a regulator of neuronal pathways which vary in the male population and underlie subtle sex-linked biases (2).