Product description
8-Oxoguanine glycosylase (OGG1) is an enzyme responsible for the removal of 8-oxoguanine (8-oxoG), a mutagenic base byproduct that emerges as a result of reactive oxygen species (ROS) exposure. The action of OGG1 involves lyase activity for chain cleavage. Two major groups of alternative splice variants exist for this gene. Type 1 variants end with exon 7 and type 2 variants end with exon 8. The N-terminal region for all variants is the same. This region contains a mitochondrial targeting signal that is necessary for mitochondrial localization. Several alternative splice variants for OGG1 have been identified, yet the nature of every variant is not fully understood.
Specifications
Applications
IHC, WB
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Supplier
Epigentek
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
-20°C

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OGG1 Polyclonal Antibody

A-6703-100

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OGG1 Polyclonal Antibody

A-6703-100

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