LSD1 Antibody
LSD1 is a nuclear homolog of amine oxidases and functions as a histone demethylaseand transcriptional corepressor. LSD1specifically demethylates histone H3 lysine 4,which is linked to active transcription. LSD1 is highly conserved between organismsranging from the fission yeast saccharomyces pombe to humans. LSD1 associates withother histone-modifying enzymes such as histone deacetylases and methyltransferases. In concert with transcription repression, loss of LSD1 function leads to derepression ofgenes regulated by Co-REST, a protein involved in gene silencing and a member ofthe LSD1.
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LSD1 Antibody
A-3018-050
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LSD1 Antibody
A-3018-050
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