Product description
The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.
Specifications
Applications
IHC, WB, IF
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Supplier
Epigentek
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
-20°C

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SMARCE1 Polyclonal Antibody

A-2716-100

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SMARCE1 Polyclonal Antibody

A-2716-100

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