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Cerebral Dopamine Neurotrophic Factor, mouse recombinant (rmCDNF)
97638.20
20 ug
€268
Product description
CDNF mouse recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing 163 amino acids and having a molecular mass of 18.5 kDa. CDNF is a member of the ARMET family and acts as a trophic factor for dopamine neurons. CDNF inhibits the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When CDNF controlled after 6-OHDA-lesioning, it reestablishes the dopaminergic function and inhibits the degeneration of dopaminergic neurons in substantia nigra. CDNF is universally expressed in neuronal and non-neuronal tissues. The highest levels in the brain are found in the optic nerve and corpus callosum. CDNF mouse is able to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons when immobilized at 5 -3 0 µg/mL on a nitrocellulose-coated microplate.
Specifications
Supplier
Biomol GmbH
Shipping & storage
Shipping condition
Room Temperature
Storage temperature
-20°C
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Cerebral Dopamine Neurotrophic Factor, mouse recombinant (rmCDNF)
97638.20
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Cerebral Dopamine Neurotrophic Factor, mouse recombinant (rmCDNF)
97638.20
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