Interleukin-36 Receptor Antagonist, mouse recombinant (rmIL-36RN)

Mouse recombinant IL36RN produced in E.coli is a single, non-glycosylated, polypeptide chain containing 154 amino acids and having a molecular mass of 17.0kDa. IL36RA belongs to the IL-1 family of proteins. IL36RA is produced as a 156 amino acids protein which holds no signal sequence, no prosegment and no potential N-linked glycosylation site but, IL36RA is secreted as a 17 kDa monomer. Cells known to express IL36Ra/IL1F5 include monocytes, B cells, keratinocytes, dendritic cells/Langerhans cells and gastric fundus Parietal and Chief cells.