Interferon Beta (IFN-b), mouse recombinant, His Tag (rmIFN-beta)

Has antiviral, antibacterial and anticancer activities. (www.uniprot.org) Mouse recombinant Interferon beta produced in E.coli is a single, non-glycosylated, polypeptide chain containing 182 amino acids (fragment 22-182) and having a molecular mass of 22 kDa. Mouse IFN beta is fused to 20 amino acid His tag at N-terminus. Interferon-beta 1b has antiviral, antibacterial and anticancer activities. Influenza A viruses not only inhibit IFN-beta gene induction but also supress Type-I IFN signaling via mechanism involving induction of the SOCS-3 protein. Intracellular bacteria and cytosolic poly (dA-dT) trigger IFN-beta responses in different human cells without requiring human ZBP1.