Mouse Anti-Human CD49f-UNLB
CD49f is the 125 kDa integrin ?6 chain which associates noncovalently with the integrin ?1 subunit (CD29) and with the integrin ?4 (CD104) chain to form, respectively, the very late antigen-6 (VLA-6) and ?6?4 integrin heterodimers. VLA-6 is expressed on thymocytes, T lymphocytes, monocytes, and platelets. CD49f/CD29 expression is upregulated on activated T lymphocytes and memory T cells. VLA-6 serves as the laminin receptor on platelets, monocytes, and T cells. VLA-6-mediated binding to laminin provides a costimulatory signal to T cells for activation and proliferation.
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Mouse Anti-Human CD49f-UNLB
9650-01
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Mouse Anti-Human CD49f-UNLB
9650-01
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