CD49f is the 125 kDa integrin ?6 chain which associates noncovalently with the integrin ?1 subunit (CD29) and with the integrin ?4 (CD104) chain to form, respectively, the very late antigen-6 (VLA-6) and ?6?4 integrin heterodimers. VLA-6 is expressed on thymocytes, T lymphocytes, monocytes, and platelets. CD49f/CD29 expression is upregulated on activated T lymphocytes and memory T cells. VLA-6 serves as the laminin receptor on platelets, monocytes, and T cells. VLA-6-mediated binding to laminin provides a costimulatory signal to T cells for activation and proliferation.
Productname
Mouse Anti-Human CD49f-UNLB
9650-01
By filling out this form, you are placing an order by e-mail. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
Productname
Mouse Anti-Human CD49f-UNLB
9650-01
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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