Nw-propyl-L-Arginine
N?-Propyl-L-Arginine is a potent and selective inhibitor of neuronal nitric oxide synthase (nNOS). N?-Propyl-L-Arginine is a competitive inhibitor of bovine nNOS having a Ki value of 57 nM.{5453} The Ki values for eNOS (bovine) and iNOS (murine) are 8.5 and 180 µM, respectively. N?-propyl-L-Arginine therefore exhibits 3,000-fold and 150-fold selectivity for the neuronal isoform versus the inducible (murine) and endothelial (bovine) isoforms of NOS, respectively.{5453}
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