15-hydroxy Prostaglandin Dehydrogenase Inhibitor Screening Kit
Cayman’s 15-PGDH Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human 15-PGDH, the enzyme that catalyzes the oxidation of prostaglandins to 15-keto metabolites with reduced biological activity. Measurement of 15-PGDH activity is carried out by monitoring the reduction of NAD+ to NADH. The reduction of NAD+ to NADH is accompanied by an increase in fluorescence at 445 nm following excitation at 340 nm. The potent and reversible 15-PGDH inhibitor ML-148 Assay Reagent is included as a positive control and inhibits 15-PGDH with an IC50 value of 11 nM.
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15-hydroxy Prostaglandin Dehydrogenase Inhibitor Screening Kit
702180-384
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15-hydroxy Prostaglandin Dehydrogenase Inhibitor Screening Kit
702180-384
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