anti-SOX-2 mouse monoclonal, IHC665, purified

SOX2, also known as SRY (Sex Determining Region Y)-Box 2, is a transcription factor that acts to regulate pluripotency of undifferentiated embryonic stem cells, and to regulate gene expression in the stomach. This diagnostic grade SOX2 IVD antibody is used to detect melanoma, testicular germ cell tumour, cervical carcinoma, lung cancer, breast cancer with basal cell phenotype, and teratoma of the central nervous system. SOX2 has been reported as a predictor of poor outcome in stage I lung adenocarcinomas. Anti-SOX2 is also used to recognize squamous cell carcinomas of the lung and gastrointestinal tract, and may be useful for detecting embryonal carcinoma.