Product description
EBS-T-001 reacts with BCL10. Having an N-terminal caspase recruitment domain (CARD), BCL10 can induce apoptosis and activate NF-kappaB. It is found on subpopulations of normal B and T cells, and is associated with MALT1, a paracaspase that, like BCL10, can be found translocated in MALT lymphoma. In such cases either BCL10 or MALT1 or both are highly expressed, depending on the site of translocation. MALT lymphomas lacking this translocation exhibit much lower levels of expression. BCL10 has been shown to be functionally conserved all the way back to zebrafish. Positive control: HepG2 cells or lymphoma.
Specifications
Host
Mouse
Clonality
Monoclonal
Clone
EBS-T-001
Supplier
PROGEN
Shipping & storage
Shipping condition
Room Temperature
Storage temperature
2-8°C

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anti-BCL10 mouse monoclonal, EBS-T-001, purified

691671

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anti-BCL10 mouse monoclonal, EBS-T-001, purified

691671

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